RNS Number:6357A
Alliance Pharma PLC
23 July 2007


For immediate release                                              23 July 2007




                          ALLIANCE PHARMA PLC
                         ("Alliance" or "the Company")


     Successful Phase III Trial Results of Isprelor in Induction of Labour

Alliance Pharma plc (AIM: APH), the speciality pharmaceutical company, is pleased to announce positive Phase III trial results for Isprelor, a vaginal tablet containing 25mg of misoprostol for the induction of labour.  The trial, conducted in more than 600 women, was a direct comparison of Isprelor versus dinoprostone, which is the current standard treatment.

As anticipated, the results showed that the two treatments were similarly efficacious; there was no statistical difference between Isprelor and dinoprostone in the ability to produce a vaginal delivery within 24 hours of commencing treatment.  However nausea, which is a well-known side effect of dinoprostone, was seen less frequently with Isprelor. No unexpected adverse events were seen with Isprelor and, most importantly, Isprelor was shown to be no more likely than dinoprostone to cause hyperstimulation of the uterus.

The induction of labour occurs in around 1 in 5 pregnancies, usually because the pregnancy continues beyond 41 weeks or because of complications, such as high blood pressure.

The Royal College of Obstetricians and Gynaecologists and other obstetricians worldwide, had called for a purpose-designed vaginal formulation of misoprostol owing to the growing off-label use of oral misoprostol tablets, which are indicated only to treat stomach ulcers.  Additionally, unlike dinoprostone, Isprelor does not require refrigerated storage, which brings added convenience.

As previously announced, Alliance intends to file for registration of Isprelor in Europe in the second half of 2008.


John Dawson, Alliance Pharma's Chief Executive, said: "The positive results from this trial will form an important part of our ongoing out-licensing negotiations for Isprelor. This pivotal trial shows that Isprelor is as effective and as well tolerated in initiating labour as the current standard treatment and we look forward to delivering to the obstetric communities the product that they called for."



For further information:


Alliance Pharma plc                 + 44 (0) 1249 466966
John Dawson, Chief Executive

Richard Wright, Finance Director
www.alliancepharma.co.uk

Numis Securities                      + 44 (0) 20 7260 1000
David Poutney
Michael Meade

Buchanan Communications       + 44 (0) 20 7466 5000
Mark Court/Rebecca Skye Dietrich




Notes to editors

About Alliance Pharma

Alliance Pharma, founded in 1996, is an AIM listed speciality pharmaceutical company based in Chippenham, Wiltshire, UK. The company has a strong track record of acquiring the rights to established niche brands and owns, or shares, the rights to 34 branded pharmaceutical products.

Alliance Pharma's products are prescribed in the treatment of a wide range of conditions and include brands used in periodontitis (a serious gum disease), the prevention of heart disease, in Parkinson's disease, in nutrition, in nasal infections, in the treatment of dermatological conditions and in childbirth. Alliance Pharma's sales are mainly prescription driven.  Its products are distributed to hospitals directly and to pharmaceutical wholesalers which service both hospital and retail pharmacies with their prescription requirements.

Alliance Pharma joined the AIM market of the London Stock Exchange in December 2003 and trades under the symbol APH.



                      This information is provided by RNS
            The company news service from the London Stock Exchange